There are preventative treatments for mountain sickness, but they may have some serious side effects and therefore alternatives have been sought.
Researchers randomized 90 healthy non-acclimated adults to receive 600mg of oral Ibuprofen or placebo every 6 hours, beginning 6 hours before rapidly ascending from an altitude of 1.000 to 4.000 meters. It was measured how often symptoms of acute mountain sickness such as headaches, dizziness, disorientation occurred and how severe they were.